Sebuah tim peneliti dari Universitas Mie di Jepang telah menemukan bahwa embrio ikan zebra awal (embrio beberapa jam setelah pembuahan) dapat dengan aman disinari dengan UVC 278 nm.
UVC-LED sekitar 260nm digunakan untuk sterilisasi karena menginduksi dan menonaktifkan kerusakan DNA dari bakteri dan virus. Sebagian besar penelitian saat ini berfokus pada efek UVC dengan panjang gelombang di bawah 240nm (207nm, 222nm, 233nm) dalam membunuh virus corona baru. Namun, ada beberapa penelitian tentang toksisitas, keamanan, dan respons organisme terhadap iradiasi UVC sekitar 280 nm.
Therefore, this time, a total of 16 irradiation doses were set in the range of 0.5 to 60 mJ/cm² using the irradiation device developed by the research group to irradiate 278 nm UVC, and zebrafish embryos were directly irradiated.
After 3 days of irradiation, the researchers evaluated the survival rate, hatching rate, heart rate, deformity rate, etc. of zebrafish embryos. The results found that all embryos remained alive under the irradiation dose below 4.5mJ/cm². However, when the dose reached 7.5 mJ/cm², the deformity rate significantly increased to 82 percent , and the survival rate decreased to 37 percent . Embryo death was observed if the dose was increased to 10 mJ/cm² and above.
Based on the above experimental results, the researchers determined that there is a biological defense system inside the zebrafish embryo, which can resist the damage caused by UVC irradiation to the greatest extent, and the limit dose that can resist UVC irradiation is 4.5 mJ/cm².
The researchers believe that the biological defense mechanism of zebrafish against UVC-induced DNA damage is that after zebrafish embryos are treated with UVC at a dose of 4.5 mJ/cm², the p53 signaling pathway in cells is immediately and urgently activated. Arrest, DNA repair, cell division/proliferation and damaged cell death in rapid response to stress. In addition, after 3 days of recovery, p53 variability was attenuated and instead activated the STAT signaling pathway, which continued to repair damaged DNA.
Hasil penelitian subjek ini memberikan dasar ilmiah untuk keamanan UVC-LED yang diterapkan pada tubuh manusia. Pada saat yang sama, tim peneliti menemukan bahwa UVC cocok untuk desinfeksi bakteri dan virus termasuk virus corona, serta desinfeksi pada akuakultur.
"Experts say UV" believes that: at the application level, the sterilization experience of UVC-LED is difficult to intuitively perceive, and consumers will have concerns about safety when using it. brings confidence.
Teknologi LED GMKJ sangat terlibat dalam sumber cahaya yang sehat dan cerdas, menyediakan pasar dengan rangkaian lengkap LED UVA UVB UVC, produk dan solusi LED IR inframerah VCSEL, dan memiliki ratusan mitra berkualitas tinggi-di dalam dan luar negeri pasar untuk bersama-sama mempromosikan penggunaan teknologi ringan untuk menciptakan kehidupan yang sehat dan cerdas. menyebabkan.